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Jackson Laboratory il22 egfp reporter mice 43
Il22 Egfp Reporter Mice 43, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/egfp+il22+mice34+transgenic/10__1158_slash_2159___8290__cd___25___0377-201-41-47
Average 86 stars, based on 1 article reviews
il22 egfp reporter mice 43 - by Bioz Stars, 2026-11
86/100 stars

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Article Title: Aryl hydrocarbon receptor ligands drive pancreatic cancer initiation and progression through pro-tumorigenic T cell polarization
Article Snippet: Although smoking is a risk factor for pancreatic adenocarcinoma (PDAC), the underlying mechanism promoting tumorigenesis and progression are unknown.. Here, we show that aryl hydrocarbon receptor ligands found in cigarette smoke, like the carcinogen 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), promote pancreatic dysplasia and PDAC progression in a mouse model of this disease.. This effect is mediated by AhR activation in CD4+ T cells, leading to their polarization to interleukin-22 (IL22) producing TH22 cells and to regulatory T cells (Treg) accumulation, ultimately driving a blunted CD8+ T cell effector response.



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Jackson Laboratory il22 egfp reporter mice 43
Il22 Egfp Reporter Mice 43, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/il22+egfp+reporter+mice+43/egfp+il22+mice34+transgenic/10__1158_slash_2159___8290__cd___25___0377-201-41-47
Average 86 stars, based on 1 article reviews
il22 egfp reporter mice 43 - by Bioz Stars, 2026-11
86/100 stars
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